In Silico Fermentation offers consulting services focused on microbial metabolic modeling to support proprietary projects of biotechnology and biomedical companies. During his academic career, Dr. Henson served as a consultant for numerous large corporations, mid-sized companies and startup ventures in the chemical and biotechnology industries. These experiences allow In Silico Fermentation to offer targeted consulting services to clients interested in data analysis, computational modeling, systems optimization and process control. My services can be beneficial during project conceptualization, experimental testing, data interpretation, process scaleup and manufacturing operations.

Fermentation Process Simulation

In Silico Fermentation offers world-class consulting capabilities in dynamic metabolic modeling of biochemical reactors. Dr. Henson pioneered methods for integrating genome-scale metabolic reconstructions and process-relevant transport mechanisms into time- and spatially-varying fermenter models. In addition to providing a powerful computational platform for fermentation process simulation and optimization, these models represent a valuable repository of strain and process knowledge. If you lack the in-house expertise needed to computationally simulate and analyze your microbial bioreactor, I can provide the modeling skills you need.

Microbial Community Modeling

In Silico Fermentation provides unique consulting services for metabolic modeling of natural and engineered microbial communities. Metabolic models can be systematically developed for small, engineered microbial systems as well as for large, natural communities characterized with metagenomic methods. These community models allow systems-level analyses of microbial cell factories cultured with synergistic partner strains or the impacts of health-promoting strains and disease-associated pathogens introduced into particular human microbiomes. If you need to better understand the metabolic organization, stability and function of a microbial community, I can provide the necessary modeling expertise to augment your experimental efforts.

Other Capabilities

In addition to my in silico modeling expertise, I offer consulting services in other related areas of bioprocess systems engineering. I have considerable experience in bioreactor control ranging from simple PID methods to more sophisticated model-based approaches. My expertise also includes the development and application of optimization methods for batch, fed-batch, continuous and multiphase fermenters. Whatever your fermentation engineering needs, I likely can provide the expertise required to advance your project.

Please contact me to discuss your consulting needs and learn more about my technical capabilities!