Applying microbial system principles to challenges ranging from renewable chemical production to microbiota-associated diseases
I am passionate about translating recent advances in microbial metabolic modeling to industrial practice. I believe that in silico modeling can accelerate innovation and expand applications of microbial technologies that benefit society.
About In Silico FermentationDynamic metabolic models for fermentation process simulation, estimation, control and optimization
Combined metabolic-transport models of bubble column bioreactors for upgrading waste gases to platform chemicals
Multispecies metabolic models to design, simulate and optimize microbial consortia for diverse bioconversion applications
Spatiotemporal metabolic models to predict species organization and interaction in natural and engineered biofilms
Community metabolic models to translate measured taxa compositions into predicted metabolic capabilities
Sample-specific metabolic models to differentiate healthy and disease states in diverse human microbiomes
Founder and Principal
February 18, 2025
In Silico Fermentation is pleased to announce the free release of STBRsim Version 2.0, a MATLAB application that streamlines the development of dynamic metabolic models for bioreactor simulation. Given a genome-scale metabolic model of the target strain, the App allows the definition of the growth medium, growth-limiting substrates and secreted products along with their uptake […]
January 30, 2025
We are pleased to report that our suite of free MATLAB applications that provide state-of-the-art microbial metabolic modeling and simulation tools have reached a milestone of 1,000 downloads. We develop these free apps by modifying and generalizing proprietary modeling tools we have developed for industrial clients. Our hope is that these apps will allow industrial […]
January 15, 2025
In Silico Fermentation is pleased to announce the release of STBRtutorial, a free MATLAB application that provides two step-by-step tutorials that demonstrate how operating policies affect stirred tank bioreactor (STBR) dynamic behavior. Using a simplified metabolic model of Escherichia coli central metabolism, students are guided through an intuitive workflow in which they consider important aspects […]
