Genome-scale metabolic reconstructions are ideal platforms to develop rigorous dynamic simulations of stirred tank bioreactors (STBRs). While the research literature contains numerous computational methods for dynamic flux balance analysis (DFBA), available modeling tools are not well suited for industrial practitioners who typically wish to perform bioreactor simulations with minimal coding effort. To address this theory-practice gap, I am developing a flexible MATLAB application for dynamic STBR simulation based on microbial metabolic reconstructions. The application places the power of advanced DFBA methods on your Windows desktop in the form of a user-friendly GUI. Rather than writing and debugging code, the user can easily configure the application to quickly generate simulation results.
Please contact me by email if you wish to learn more about this application under development.
